This medicine is great in use with an oral medicine. It helps ease the edge off until the medicine has time to kick in. Orajel is one of those tried and true medicines that your parents used on you and everyone recommends it! I am no exception to the rule. I recommend it as well. It works really well. It really helps to calm a teething baby. If you have been through teething then you know how hectic these times can be. Some kids get it worse than others. I keep a tube of this in my bathroom and also another one in my kids diaper bag. It is a must that I always have it on hand because you never know when a teething fit is going to strike. It doesn't last very long. I sometimes wish it lasted a lot longer but I am overall just happy that it works period and that there is some type of relief for this hard time for babies. The only thing is not knowing when to give it to a baby. The good thing about this is that it will not harm them if you give it to them quite often. They may not like the way it feels at first but they will soon realize the pain easing.