I was in a motorcycle accident a few years ago, which knocked out a lot of my teeth. After trying a bunch of different types of denture adhesive creams, I know for a fact now that I will never use anything but Super PoliGrip. It has a very strong hold without hurting my mouth and it actually costs less than a lot of the other products out there right now.
What matters most to me and everyone else I know with dentures is that the cream holds the teeth in place to avoid random embarrassments. This stuff handles any type of food and really only moves around when I need it to. I also really like that I can take it off with no problems at all, so I really don't have to plan to spend any additional time in the bathroom at night.
No one wants to wear dentures, but if you have to, you have to at least try Super PoliGrip because chances are you will like it as much as I do. I am a huge fan and plan on using this stuff for the rest of my life. There really aren't too many other products that I can say that about.